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Translational and innovative nanomedicine laboratory

Texas A&M University College of Engineering

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The Translational and Innovative Nanomedicine lab was started by Dr. Isaac Adjei in 2019 and shut in 2024.
Lab group Pciture_fall 2021

TRAIN Lab members – Fall 2021

Our lab’s mission was to employ engineering approaches to understand human diseases and develop novel therapeutic strategies.
Our lab’s focus was to understand nanoparticle-cell interactions as well as the application of nanoparticles in the treatment of various diseases such as bone metastasis and glioblastoma.

 

Research overview

Engineering the tumor microenvironment

Techniques for NP targeting to tissues

 

 

 

 

 

 

Modulating inflammation and hypoxia in neurological disorders

  • Presentation1
    Atomic force microscopy micrograph of nanoparticles
  • A549 MSC and NK cells spheroid 1 (Snapshot 1) (2)
    Interaction of NK cells (red) with cancer (green) and MSC (blue) multi cell-type spheroid
  • Adjei_2
    MSCs (red) in the hypoxic core of cancer spheroid (blue)
  • F3 lung-3 zoom z stack (Snapshot)
    Nanoparticles (red) in lung tissue
  • 40 nm 24 hours z stack-2 (Snapshot)
    Nanoparticles (red) in natural killer cells

August 2019 – The translational and innovative nanomedicine lab starts at Texas A&M University

Interaction of natural killer cells (red) with spheroid made up of cancer cell (green) and mesenchymal stem cell (blue).

Accumulation of nanoparticles into the bones of mouse.

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